The Inomed C3 CryoSystem allows the physician to “put the pain on ice”, freezing the nerve responsible for the chronic pain in the spinal column region. The basic principle of cryotherapy requires that the affected nerve is located and identified using imaging and visual techniques and then the CryoSystem probe starts the process and freezes the nerve to approximately -60 °C. Freezing causes axonotmesis of nerves (disruption of the axon), but the connective tissue remains intact and allows the nerve to regenerate. In view of the precise targeting of the sensory nerve, there is no direct risk from cryotherapy to the nerves responsible for motor activity and sensitivity.